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Biology In Motion - Storyboard, Version 1

This storyboard design was created by Delle Rae Maxwell. You can find more of her work on her website at www.dellerae.com.

1. Guy playing outside in the sun.			2. Zoom in closer to see a spot on his shoulder. His motion can freeze when we get close enough. How will his immune system respond to this skin cancer?
3. Dissolve to body diagram of lymph system. Can see schematic of tumor, motion of dots to lymph node and back.			4. We move in closer to see what is going on. Circulation of dendritic cells to nearby lymph node, activated T cells return to tumor site.
5. A closer look. Circles dissolve in. Animation in circles are closer views of cells.			6. Area at tumor site zooms up even larger, to cover screen. Show process of dendritic cells sampling tumor antigen.
7. When dendritic cells are ready to leave the area shown in circle, zoom circle back out and show motion towards lymph node along green path.			8. Second circle zooms up. Now show second animation with naive T cells being activated by dendritic cells.
9. When activated T cells are ready to leave lymph node, zoom out circle. Grayed out circle on left activates again. How does the T-cell know where to find the tumor?			10. In the vastness of the circulatory system, how do T-cells know how to find the tumor? Animation of travel through the bloodstream with the T-cells.
11. It is like stepping into a tornado with blood cells rushing by at high speeds. How can the cells slow down and stop in this environment? How do the cells know where to stop? Is there a trail of signals?			12. Tools that can animate/show processes that can't normally be seen. How we can study how the T-cell slows down and stops. Labscape, Metagraph.
13. Multiple views can show simultaneous visualizations of aspects of the process.			14. The data can be seen in multiple representations, from schematic to photgraphics to modeled in 2D or 3D.
15. The user interface is customizable for different types of simulation and visualization.			16. Recap of goals of understanding the immune system, biological systems in general. Also role in developing therapies. Predictive approach to validation of drug candidates and diagnostic evaluation of disease processes. (Enabling our guy to get back to playing).